Innovation Newsletter

The MUSIQ network shares updates and highlights on the project’s progress, results and ESR’s activities, with a focus on the latest innovation related to multiphoton microscopy and bioimaging through dedicated online Innovation Newsletters.

MUSIQ Innovation Newsletter n. 3 | October 2021

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Prospects of stimulated Raman scattering in pharma research

Before a novel medicine can be introduced on the market, it needs to undergo a drug development process which today on average consists of six stages. The drug development process from target discovery to the launch can  take up to 15 years. Read more

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Light sources for CARS microscopy

In coherent anti-Stokes Raman scattering (CARS) microscopy two laser beams are used to produce radiation at a third wavelength when energy difference between pulses matches vibrational energy of a sample. For this vibrationally specific microscopy method it is critical to have a reliable wavelength-tunable light source to address different Raman bands. Optical parametric amplifiers (OPAs) and oscillators (OPOs) are well suited for this task. Read more

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EMCCD and sCMOS cameras for scientific imaging
A comparison of the key figures of current camera models

The emergence of faster and more sensitive scientific cameras allows to acquire images with unprecedented sensitivity and speed. This is particularly important for applications in life sciences where techniques like Raman imaging require low-noise detectors while other techniques like fluorescent correlation spectroscopy rely on frame rates in the upper kilohertz range. To obtain meaningful data it is therefore essential to choose the scientific camera according to the experimental conditions.  Read more

MUSIQ Innovation Newsletter n. 2 | March 2021

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Broadband laser sources for ultrafast spectroscopy

The continuous progress in laser technology along with technical advances and conceptual breakthroughs, expand the application potential of Ultrafast Spectroscopy. Read more

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Pulse shaping techniques for ultrafast spectroscopy

This section focuses on programmable femtosecond pulse-shaping techniques for multidimensional ultrafast spectroscopy. Read more

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Resources for improving data acquisit/newsletter/ion and coherence characterization in ultrafast spectroscopy

This section focuses on: 1. eliminating heat-induced signals by controlling pulse spectra through pulse shaping, 2. compressive sensing to shorten the data acquisition time, and 3. simultaneous frequency and time resolution using time-frequency transforms.  Read more

MUSIQ Innovation Newsletter n. 1 | October 2020

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Laser sources for Coherent Raman Scattering Microscopy

State of the art and new technologies – How to choose the best laser source for your SRS experiments

The laser source is arguably the core component in any CRS experiment. In this brief article we explain what the most common laser sources for CRS microscopy are and try to give guidelines for their selection. Read more

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Light sources for harmonic generation and multiphoton fluorescence microscopy

This section informs about the latest laser sources and their requirements for biophotonics applications. Specifically, the field of multiphoton microscopy (MPM) was subject to vast developments in recent years, pushed by the development of pulsed laser sources. This article will provide an overview of specific requirements of MPM experiments, and therein requirements for the laser sources themselves. Read more